Careers at Organovo

Organovo Inc. is an early-stage biotechnology company that is developing and utilizing highly customized 3D human tissues as dynamic models of healthy and diseased human biology for drug development.

We use proprietary technology to build functional 3D human tissues that mimic key aspects of native human tissue composition, architecture, function and disease. Our advances include cell type-specific compartments, prevalent intercellular tight junctions, and the formation of microvascular structures. We believe these attributes can enable critical complex, multicellular disease models that we will use to develop clinically effective drugs for selected therapeutic areas.

Position Overview:

Organovo is focused on the utilization of high fidelity, human 3D cell models for target identification, validation and drug discovery across a range of therapeutic areas, including gastrointestinal (GI) disease biology as one of the initial targets. We are looking for a scientific expert to serve as the team leader to deliver on target identification and drug development programs in the GI therapeutic area. The Principal Scientist will drive the strategy for development of GI discovery programs and will apply emerging translational science and the company’s vision and corporate strategy as they lead the development of 3D approaches and GI target selection.

Key Responsibilities:

• Develop 3D models, identify worthy targets, and advance relevant discovery programs into the clinic through interfacing with collaborators and internal scientists
• Define rigorous go/no-go decisions with a focus on hypothesis-driven, genetic, biomarker and metabolomics-based methodology
• Drive collaborations with internal groups and external partners, including CROs and academia for tissue procurement, sample handling, and data generation
• Interface with research teams and support projects relating to GI inflammation
• Apply skillsets in molecular and cell biology to contribute to multiple programs in GI drug discovery

Key Qualifications:

• PhD, MS-level candidate with robust expertise in the field would be considerable
• 8+ years of life science experience, 5+ within a biotech/pharma industry setting preferred
• Drug discovery experience in GI and/or GI Inflammatory Diseases
• Knowledge of and experience with GI physiology, immunology, and enteric nervous system
• Knowledge and appreciation of the GI landscape as it relates to existing and emerging scientific insights, opportunities, and unmet medical needs
• Network of relationships with key opinion leaders in the field of GI disease

Management and Leadership Qualifications:

• At least 2 years supervisory experience, leading both PhD level scientists and research associates
• Proven team leader who can engender credibility and confidence within and outside the company as well as inspire, motivate, and drive results
• Track record of successful leadership, management and development of small teams
• Demonstrated embracement of diversity and inclusion in the workplace
• Excellent communication skills, both written and verbal, with the ability to persuasively convey both ideas and data
• Ability to distill complex issues and ideas down to simple comprehensible terms

If you are interested in one of our current opportunities, please apply here.

Please be aware that scams targeting job seekers are increasing. Information on how to identify and report employment scams is available from a variety of sources, including Federal Trade Commission on Job Scams and Better Business Bureau on Employment Scams.

Organovo, Inc., does not use free email services such as Gmail, Hotmail or Yahoo, to communicate with prospective job applicants. If you have a question as to whether a job posting comes from Organovo, Inc., please email us at hr@organovo.com.

Organovo Inc. is an early-stage biotechnology company that is developing and utilizing highly customized 3D human tissues as dynamic models of healthy and diseased human biology for drug development.

We use proprietary technology to build functional 3D human tissues that mimic key aspects of native human tissue composition, architecture, function and disease. Our advances include cell type-specific compartments, prevalent intercellular tight junctions, and the formation of microvascular structures. We believe these attributes can enable critical complex, multicellular disease models that we will use to develop clinically effective drugs for selected therapeutic areas.

Position Overview:

Organovo is focused on the utilization of high fidelity, human 3D cell models for target identification, validation and drug discovery across a range of therapeutic areas. We are seeking a skilled Research Associate to assist with cell assay development and interrogation of disease biology to support target identification and drug discovery. The successful candidate will play a key role in the ongoing development of Organovo’s scientific technology platform.

Key Responsibilities:

• Assist in the development and optimization of 3D primary cell-based assays
• Conduct critical biomarker and proliferation assays (ELISA, qPCR)
• Maintain detailed experimental records via ELN entries
• Present and explain data results and conclusions at team meetings
• Interact with CROs to assist with oversight of external studies
• Prepare and solubilize compounds for testing
• Develop or apply expertise in primary cell culture, bioprinting, and spheroid culture

Key Qualifications:

• BA/BS in biological sciences
• 2+ years of cell biology experience, biotech/pharma industry experience preferred
• Cell culture experience required, experience with primary cells, co-culture systems and/or 3D cell culture models preferred
• Hands-on experience with a broad range of gene and protein expression techniques desired (ELISA/MSD, qRT-PCR, NGS, IHC)
• Experience with high-throughput screening assays and automation is a plus
• Ability to independently execute experiments and perform data analysis (excel, prism etc.)
• Strong organizational and documenting skills with keen attention to detail
• Exceptional communication, critical thinking and problem-solving skills
• Creativity and the ability to work with an interdisciplinary team to achieve technical and corporate milestones

If you are interested in one of our current opportunities, please apply here.

Please be aware that scams targeting job seekers are increasing. Information on how to identify and report employment scams is available from a variety of sources, including Federal Trade Commission on Job Scams and Better Business Bureau on Employment Scams.

Organovo, Inc., does not use free email services such as Gmail, Hotmail or Yahoo, to communicate with prospective job applicants. If you have a question as to whether a job posting comes from Organovo, Inc., please email us at hr@organovo.com.

Organovo Inc. is an early-stage biotechnology company that is developing and utilizing highly customized 3D human tissues as dynamic models of healthy and diseased human biology for drug development.

We use proprietary technology to build functional 3D human tissues that mimic key aspects of native human tissue composition, architecture, function and disease. Our advances include cell type-specific compartments, prevalent intercellular tight junctions, and the formation of microvascular structures. We believe these attributes can enable critical complex, multicellular disease models that we will use to develop clinically effective drugs for selected therapeutic areas.

Position Overview:

Organovo is seeking a skilled Scientist that will design, build and characterize human primary 3D tissues capable of reproducing disease phenotypes to identify targets and discover drugs with improved efficacy in the clinic.

Key Responsibilities:

• Design and build human primary cell 3D tissue constructs for drug discovery
• Utilize a battery of assay technologies to evaluate effects of modulators on disease phenotype in tissue constructs, including ELISA, qPCR, viability, and histology.
• Identify and implement new assay technologies that impact assay value, throughput and/or performance
• Primary cell culture and maintenance of 3D tissues
• Develop strategies that link our 3D models closely to the clinical disease phenotype
• Summarize data and report results to supervisor, internal and external groups 
• Adhere closely to defined timelines to meet internal goals, often dealing with multiple projects in parallel
• Provide training and supervision to junior staff, as needed

Key Qualifications:

• Ph.D. with approximately 1-5 years or Masters degree with 5+ years training in cell or molecular biology
• Experience in culture of primary human cells (e.g. Cardiac, Skin)
• Candidates should display excellent written and verbal communication skills as well as participating as part of a dynamic team
• Candidates may be responsible for managing a small team of scientists and/or research associates and must be able to function independently, think critically and creatively, and be technically innovative to design and build new in vitro models
• Although not essential, candidates with experience in liver or lung cell primary cell culture, biomaterial fabrication and characterization, and relevant industry or biotechnology experience in tissue engineering, stem cell biology, iPSC generation and 3D tissue modeling are preferred.

If you are interested in one of our current opportunities, please apply here.

Please be aware that scams targeting job seekers are increasing. Information on how to identify and report employment scams is available from a variety of sources, including Federal Trade Commission on Job Scams and Better Business Bureau on Employment Scams.

Organovo, Inc., does not use free email services such as Gmail, Hotmail or Yahoo, to communicate with prospective job applicants. If you have a question as to whether a job posting comes from Organovo, Inc., please email us at hr@organovo.com.

Organovo Inc. is an early-stage biotechnology company that is developing and utilizing highly customized 3D human tissues as dynamic models of healthy and diseased human biology for drug development.

We use proprietary technology to build functional 3D human tissues that mimic key aspects of native human tissue composition, architecture, function and disease. Our advances include cell type-specific compartments, prevalent intercellular tight junctions, and the formation of microvascular structures. We believe these attributes can enable critical complex, multicellular disease models that we will use to develop clinically effective drugs for selected therapeutic areas.

Position Overview:

Organovo is seeking a skilled Scientist that will characterize, optimize, and validate human primary 3D tissues capable of reproducing disease phenotypes to identify targets and discover drugs with improved efficacy in the clinic.

Key Responsibilities:

• Generate human primary cell 3D tissue constructs for drug discovery
• Utilize a battery of assay technologies to evaluate effects of modulators on disease phenotype in tissue constructs, including ELISA, qPCR, viability, and histology.
• Identify and implement new assay technologies that impact assay value, throughput and/or performance
• Primary cell culture and maintenance of 3D tissues
• Develop strategies to assess linkage of 3D models to clinical disease phenotypes
• Summarize data and report results to supervisor, internal and external groups 
• Work internally and with academic partners to Adhere closely to meet internal goals and timelines, often dealing with multiple projects in parallel
• Participate in the preparation of publications, grant applications, and reports related to research projects
• Provide training and supervision to junior staff, as needed

Key Qualifications:

• Ph.D. with approximately 1-5 years or Masters degree with 5+ years training in cell or molecular biology
• Experience in culture of primary human cells (e.g. Liver, Lung)
• Candidates should display excellent written and verbal communication skills as well as participating as part of a dynamic team
• Candidates may be responsible for managing a small team of scientists and/or research associates and must be able to function independently, think critically and creatively, and be technically innovative to design and build new in vitro models
• Although not essential, candidates with experience in liver or lung cell primary cell culture, biomaterial fabrication and characterization, and relevant industry or biotechnology experience in tissue engineering, stem cell biology, iPSC generation and 3D tissue modeling are preferred.

If you are interested in one of our current opportunities, please apply here.

Please be aware that scams targeting job seekers are increasing. Information on how to identify and report employment scams is available from a variety of sources, including Federal Trade Commission on Job Scams and Better Business Bureau on Employment Scams.

Organovo, Inc., does not use free email services such as Gmail, Hotmail or Yahoo, to communicate with prospective job applicants. If you have a question as to whether a job posting comes from Organovo, Inc., please email us at hr@organovo.com.